Dirección Xeral de Saúde Pública

Results of implementation of Nirsevimab in Galicia.
Campaign started on week 46.

RSV season started on week .

1. Main results at a glance

Cumulative hospitalization rate in infants during the 1st RSV season (for those immunized with Nirsevimab).
Cumulative hospitalization rate in infants during the 2nd RSV season (those NOT eligible for Nirsevimab).
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to 17-11-2024. Catch-up cohort of infants born between April and September.
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to 17-11-2024. Cohort of infants in their 2nd RSV season.

2. Vaccination coverage

Immunized in campaign: infants born after September 25th (up to 17-11-2024).
92.3%
With a total of 1,984 immunized infants.
Catch-up vaccinated: infants born between April 1st and September 2024 (up to 17-11-2024).
84.8%
With a total of 5,676 immunized infants.
High-risk infants born between October 1st, 2023 and March 31st, 2024.
100%
With a total of 283 immunized infants.

3. Evolution of the RSV epidemic wave

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Total population positivity percentage (RSV) in Galicia, in seasons 2022-23 and 2023-24 up to 17-11-2024.

Virus circulation is measured by positivity percentage to all samples sent to the microbiology laboratories of the Galician Health Service. This percentage is estimated by dividing all positive samples between all negative samples. Following the Galician Epidemiology Butlletin vol XXIII number 6 a percentage of 3% is consider a threshold for the epidemic wave in season 2023-24.

4. RSV hospitalization

4.1 Immunized with Nirsevimab

a) Cohort of infants born between April and September

For current season 2023-24, it includes catch-up (infants born between April 1 and September 24, 2023); for the comparison with previous seasons, data was collected from infants born between April 1 and September 30 of the start of season year.

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Weekly RSV hospitalization rate for seasons 2023-24 and 2024-25 in Galicia, up to 17-11-2024, and median (range) for seasons 2017-18, 2018-19 and 2019-20. Cohort of infants born between April and September.
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to 17-11-2024. Cohort of infants born between April and September

b) Infants under 2 months of age

For the current season, this group is dynamic and will begin with a high proportion of catch-up infants; as weeks go by, the percentage of infants immunized at birth will increase, until reaching 100% on 25 November (epidemiological week 47).

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Weekly RSV hospitalization rate for seasons 2023-24 and 2024-25 in Galicia, up to 17-11-2024, and median (range) for seasons 2017-18, 2018-19 and 2019-20. Infants under 2 months.
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to 17-11-2024. Infants less than 2 months.

c) Infants under 6 months of age

Also for this group, at the beginning of the wave the majority of infants come from the catch-up group.

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Weekly RSV hospitalization rate for seasons 2023-24 and 2024-25 in Galicia, up to 17-11-2024, and median (range) for seasons 2017-18, 2018-19 and 2019-20. Infants under 6 months.
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to 17-11-2024. Infants less than 6 months.

4.2 Not immunized with Nirsevimab

a) Cohort of infants born between April and March in their 2nd RSV season

For 2023-24 are infants born between 1 April 2022 and 31 March 2023. Same criteria was applied to the previous seasons cohort.

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Weekly RSV hospitalization rate for seasons 2023-24 and 2024-25 in Galicia, up to 17-11-2024, and median (range) for seasons 2017-18, 2018-19 and 2019-20. Cohort of children born between April and March in their 2nd RSV season.
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to 17-11-2024. Cohort of children born between April and March in their 2nd RSV season.

b) Infants under 2 years of age

Infants under 2 years at the start of hospitalization.

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Weekly RSV hospitalization rate for seasons 2023-24 and 2024-25 in Galicia, up to 17-11-2024, and median (range) for seasons 2017-18, 2018-19 and 2019-20. Infants under 2 years.
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to 17-11-2024. Infants under 2 years.

c) Infants 2 to 5 years old

Infants between 2 and 5 years at the start of hospitalization.

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Weekly RSV hospitalization rate for seasons 2023-24 and 2024-25 in Galicia, up to 17-11-2024, and median (range) for seasons 2017-18, 2018-19 and 2019-20. Children 2 to 5 years old.
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to 17-11-2024. Children 2 to 5 years old.

d) Adults older than 60 years

Adults older than 60 years at date of admission.

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Weekly RSV hospitalization rate for seasons 2023-24 and 2024-25 in Galicia, up to 17-11-2024, and median (range) for seasons 2017-18, 2018-19 and 2019-20. Older than 60 years.
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to, 17-11-2024. Older than 60 years.

e) Adults older than 80 years

Adults older than 80 years at date of admission.

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Weekly RSV hospitalization rate for seasons 2023-24 and 2024-25 in Galicia, up to 17-11-2024, and median (range) for seasons 2017-18, 2018-19 and 2019-20. Older than 80 years.
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to 17-11-2024. Older than 80 years.

5. Primary care assistance for acute bronchiolitis in children under 2 years of age

a) Cohort of births between April and September

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Weekly consultation rate for acute bronchiolitis in Galicia, by season. Cohort of infants born between April and September.
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Cumulative weekly consultation rate for acute bronchiolitis in Galicia, by season. Cohort of infants born between April and September.

b) Infants under 2 months of age at the consultation date

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Weekly consultation rate for acute bronchiolitis in Galicia, by season. Infants less than 2 months.
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Cumulative weekly consultation rate for acute bronchiolitis in Galicia, by season. Infants less than 2 months.

c) Infants under 6 months of age at the consultation date

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Weekly RSV hospitalization rate for seasons 2023-24 and 2024-25 in Galicia, up to 17-11-2024, and median (range) for seasons 2017-18, 2018-19 and 2019-20. Infants under 6 months.
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Cumulative weekly RSV hospitalization rate in Galicia, by season, up to 17-11-2024. Infants less than 6 months.

d) Infants under 2 years of age at the consultation date

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Weekly consultation rate for acute bronchiolitis in Galicia, by season. Infants less than 2 years.
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Cumulative weekly consultation rate for acute bronchiolitis in Galicia, by season. Infants less than 2 years.
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